Solv Wellness Hot Flash Relief is a once-daily capsule formulated with Menofelis®, a plant-based extract from rhapontic rhubarb root, backed by 6 clinical studies and 30+ years of use in menopausal symptom management. It works with the body’s temperature regulation pathway to reduce the frequency and intensity of hot flashes and night sweats without raising estrogen levels or introducing hormones. In clinical research, Menofelis® reduced hot flashes by up to 90% vs. placebo in 12 weeks. FSA/HSA eligible.

As estrogen declines during perimenopause and menopause, the body’s internal thermostat becomes more sensitive—triggering the sudden heat spikes and nighttime sweats many women know all too well. The active ingredient, Menofelis®, works with the receptor pathway linked to temperature control (ER-β), helping recalibrate that response. It does not mimic estrogen or raise estrogen levels nor does it interact with the receptor linked to breast or uterine tissue (ER-α). The result is fewer flashes during the day and cooler, more uninterrupted nights without hormones.

Many women notice improvements in hot flash frequency and intensity within 4 weeks of consistent daily use. By 12 weeks, clinical data shows most participants experienced fewer flashes, less intense temperature swings, and better sleep. Benefits build with continued use. Give it the full 12 weeks before evaluating and be sure to take it daily.

Both. Hot flashes and night sweats are the same underlying response (the body’s overreactive thermostat) but triggered at different times of day. Menofelis® targets the temperature regulation pathway driving both hot flashes and night sweats. In clinical studies, participants reported improvements in night sweats alongside daytime hot flash reduction, with many noting more restful, uninterrupted sleep within the first 4 weeks and continued benefit through 12 weeks.

Yes, Solv Wellness Hot Flash Relief is non-estrogenic and is a plant-based option, so it’s safe for those who don’t wish to use estrogen products. The body uses estrogen receptors like small signaling switches. One receptor (ER-β) is associated with temperature regulation and nervous system signaling. That is the receptor Solv Wellness Hot Flash Relief targets. It does not raise estrogen levels or bind to the receptor linked to tissue growth in the breasts and the uterus (ER-α). This distinguishes it from phytoestrogens like soy isoflavones, which mimic estrogen and may not be appropriate for women with hormone-sensitive histories. However, we always recommend speaking with your healthcare professional before using it if you have any concerns. 

Perimenopause is when some women may start experiencing hot flashes, which can sometimes occur years before their last period. Menofelis® has been studied across the full hormonal transition, and Solv Wellness Hot Flash Relief is appropriate for use in both perimenopause and menopause. Starting consistent daily use when symptoms first emerge means you’re supporting your temperature regulation before symptoms escalate rather than catching up to them.

Take one capsule daily, with or without food. Timing is flexible—morning or evening, both work. Most women find it easiest to pair it with an existing daily habit, like brushing teeth or morning coffee, so they don’t forget. Set a phone reminder for the first few weeks until it becomes routine. Consistent daily use is what drives results.

Yes. Menofelis® has been used clinically for over 30 years with a well-established safety profile in menopausal women, particularly as a regulated herbal medicinal product across Europe. It is non-hormonal, so it does not carry any long-term risks associated with estrogen-based therapies. Solv Wellness Hot Flash Relief is designed for ongoing daily support through perimenopause and menopause—there is no need to cycle off or take breaks.

Solv Wellness Hot Flash Relief is non-hormonal, making it a common choice for women bridging to or from hormone therapy, or managing residual symptoms alongside it. In fact, a 2025 retrospective cohort study found no higher breast cancer diagnosis rate vs. non-users or HRT users. If you take prescription medications, particularly for blood pressure, thyroid, or cholesterol, or medications for hormone-sensitive conditions, we always recommend speaking with your healthcare professional before adding a supplement to your routine. For most women on standard supplement stacks, there are no known adverse events.